(+)-(1S,5R,10S)-11,11-Dimethyl-4-oxatricyclo[8.4.0.01,5]tetradecane-3,12-dione
نویسندگان
چکیده
The title compound, C(15)H(22)O(3), was prepared via amino-acid-promoted Robinson annulation followed by tandem Pd/C-mediated hydrogenation and oxidative cyclization. This product was instrumental in determining the feasibility of a stereocontrolled hydrogenation in which the directing hydroxyl group is adjacent to the 6-7-ring network and its olefinic component. The asymmetric unit consists of a single mol-ecule with normal geometric parameters. The absolute configuration was assigned based on the known enanti-omeric prescursor. Inter-molecular C-H⋯O inter-actions link each mol-ecule with four neighboring mol-ecules.
منابع مشابه
Neoirietriol
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